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HMH Convalescent Plasma Work for COVID-19 Treatments Enters Next Phase of Study

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What you need to know

More details about The Convalescent Plasma Program

The convalescent plasma program at Hackensack University Medical Center identifies the “super donors” with the greatest levels of highly-neutralizing antibodies, independently validated, as determined through methodology developed by CDI experts.

What may separate the Hackensack-based trial from other convalescent plasma trials across the nation is the application of higher levels of highly-neutralizing antibodies from survivors’ plasma – those of the so-called “super donors” whose natural defenses may hold the secret to more successfully treating the infection.

The new Phase 2 study is for infusing this potentially valuable serum into patients with early-stage COVID-19 infection who have at least one major risk factor for serious disease, in an outpatient setting. The goal is to treat the patients in the first 96 hours – with the aim to prevent hospitalization entirely.

Convalescent plasma treatments have previously been used to fight other viral outbreaks, including those of severe acute respiratory syndrome (SARS), caused by a virus that’s a cousin to the one responsible for COVID-19, and which sickened thousands in 2002-2003.

The program in Hackensack was profiled early in the pandemic by major media outlets, including the TV newsmagazine 60 Minutes.